4-Oxospiro[benzopyran-2,4'-piperidines] as class III antiarrhythmic agents. Pharmacological studies on 3,4-dihydro-1'-[2-(benzofurazan-5-yl)- ethyl]-6-methanesulfonamidospiro[(2H)-1-benzopyran-2,4'-piperidin]-4-on e (L-691,121)

J Med Chem. 1992 Oct 16;35(21):3973-6. doi: 10.1021/jm00099a028.

Authors

J M Elliott¹, H G Selnick, D A Claremon, J J Baldwin, S A Buhrow, J W Butcher, C N Habecker, S W King, J J Lynch Jr, B T Phillips, et al.

Affiliation

¹ Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486.

PMID: 1433205
DOI: 10.1021/jm00099a028

No abstract available

MeSH terms

Animals
Anti-Arrhythmia Agents / chemistry
Anti-Arrhythmia Agents / pharmacology*
Dogs
Piperidones / chemistry
Piperidones / pharmacology*
Spiro Compounds / chemistry
Spiro Compounds / pharmacology*
Structure-Activity Relationship

Substances

Anti-Arrhythmia Agents
Piperidones
Spiro Compounds
L 691121